The United States developed the National Seed Strategy for Rehabilitation and Restoration (National Seed Strategy, 2015) to foster a science-based, collaborative approach to improving the use and availability of native plants needed for restoration. The National Seed Strategy is written by conservation and restoration experts of the Plant Conservation Alliance. The Seed Strategy is recognized in the Department of Interior (DOI) 2021 Climate Action Plan as a critical tool for tackling the climate crisis and the Bipartisan Infrastructure Law includes implementation of the National Seed Strategy in its funding activities. The four goals of the National Seed Strategy foster increased coordination to accelerate the pace, scale, and quality of restoration across, tribal, state, local, and private lands. From reclaimed mines to wildlife corridors, the National Seed Strategy provides a charge and action plan for restoring and rehabilitating the Nation’s spectacularly diverse natural areas. In the first five years, the National Seed Strategy has built significant momentum to guide ecological restoration across large landscapes by helping partners work more effectively together to build a continuous supply of locally adapted plants to restore U.S. lands. The coming decade challenges us to intensify cross-sector efforts to meet an increasing demand for locally adapted seed to restore native plant communities altered by natural or human-caused events, especially important, given the greater frequency and intensity of wildfires, hurricanes, and floods. Our work is only beginning and harnessing the current momentum and increasing collaboration through the National Seed Strategy is vital to getting the right seed, in the right place, at the right time.