Mexico Federal Highway 2 (HW2) is a road that runs across all of Northern Mexico, somewhat parallel to the international border. In the state of Sonora, HW2 bisects the incredibly diverse Sky Island Region, an area where temperate species like black bear and mule deer coexist with tropical species like ocelots and coati. In this region, HW2 also intersects the USFWS Northwestern Jaguar Recovery Unit habitat probability model in two places. For the past 6 years Wildlands Network and partners have been building the science needed to inform corresponding government authorities about the issue at hand and support specific recommendations in key corridors. In 2019, a reform to Sonora’s Territorial Ordinance and Urban Development Law was approved, requiring all highway projects in the state to include appropriate mitigation structures from the design stages of the project, whether it be a new highway or the improvement of an existing one. This has been a slow but great step for connectivity conservation in Northern Mexico. We are currently working with the Secretariat of Infrastructure and Urban Development in updating the Regional Territorial Ordinance Programs for Sonora. These documents are the resource that environmental consultants need to turn to when hired by constructing companies. These documents will now include information about ecological corridors, endangered and protected species, mitigation infrastructure characteristics, and specific recommendations and needs for key stretches of highways. Two recent jaguar sightings in the borderlands and a recent publication suggesting that there is more potential jaguar habitat in Arizona and New Mexico that previously thought highlight the need and the importance of advocating for permeable highways in the Sky Island Region of the US-Mexico borderlands.